For the study, researchers analyzed data from an ongoing study of aging that involved nearly 8,800 participants who were an average of 66 years old, a majority of whom were females.
They was given tests that measured blood pressure, cholesterol levels and body mass index (BMI), and were also asked about their smoking habits. Participants were also tested for their risks for stroke and heart disease, and were given tasks that helped measure their memory and cognitive abilities after four and eight-year follow-up periods.
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The researchers found those at the highest risk for stroke had lower scores in cognition, memory and executive processing as measured by the tasks. High blood pressure specifically was associated with lower cognitive and memory scores after the eight years, while high BMI — used to measure if a person is overweight or obese — was also tied to lower memory scores.
However across the board, smoking was associated with lower performance on all cognitive measures studied at four and eight-year intervals.
“Smoking emerged as the most consistent predictor of cognitive decline,” wrote the study’s authors, lead by Dr. Alex Dregan, a public health sciences researcher at Kings College London. The study appears in the Nov. 25 issue of Age and Aging.
The authors say their study shows that the most promising preventive approach to reduce cognitive declines should consider the potential multiple causes, such as smoking and cardiovascular risks.
“Specifically, interventions to limit cognitive decline should consider the combined effect of multiple vascular risk factors rather than focusing on the management of individual-risk factors as routinely performed in the past,” they wrote.